Pagina 5 - Equi-infos
- - November 08, 2023 314
Equine Gastric Ulcer Syndrome is well known amongst equine veterinarians.
By Dr Michael Robinson
Aetiology
EGUS is best regarded as two separate entities: Equine Squamous Gastric Disease (ESGD) and Equine Glandular Gastric Disease (EGGD)1.
The two conditions may occur either independently or concurrently in the same horse. The presence or absence of one cannot be used as a predictor for the presence of absence of the other1.
ESGD is very common (between 11-95% depending on discipline and management)1,2. The causes of ESGD are well documented and it is known to be highly responsive to routine treatment with proton-pump inhibitors, such as omeprazole1.
EGGD is becoming more widely recognised (between 16-65% depending on discipline and management)1,2 as more veterinarians seek out the pyloric region of the stomach on routine gastrocopies. Visualisation of this region may be technically challenging but is an essential part of a full gastroscopy (Figure 1). The specific causes of EGGD are
- - Juli 28, 2023 68
Hyaluronic acid
Sodium hyaluronate has been found present in the synovial fluid of all species studied. In humans it is also found in other soft connective tissues such as skin, umbilical cord, and vitreous humour as well as being present in lung, kidney, brain, and muscle tissues. Scientific understanding of the underlying properties of sodium hyaluronate started in 1934, when it was isolated from bovine vitreous humour Since the 1950s, the litterature concerning the potential therapeutic use of sodium hyaluronate in humans has grown.
The viscoelastic properties of synovial fluid in the joint are known to due to its sodium hyaluronate content. Changes in the lubricating properties of synovial fluid, lead to significant pain and loss of function.
In pathological conditions, due to acute and chronic inflammation, the synovial fluid no longer exhibits its normal rheological properties that protect the synovial tissue and cartilage from mechanical stress.
The concentration and molecular size
