Page 2 - Equi-infos
- - October 30, 2024 121
Cucurbiturils??
In the wide area of supramolecular chemistry, cucurbiturils (CBn) present themselves as a young family of molecular containers, able to form stable complexes with various guests, including drug molecules, amino acids and peptides, saccharides, dyes, hydrocarbons, perfluorinated hydrocarbons, and even high molecular weight guests such as proteins (e.g., human insulin).
Dans le vaste domaine de la chimie supramoléculaire, les cucurbituriles (CBn) se présentent comme une jeune famille de conteneurs moléculaires, capables de former des complexes stables avec divers composés, notamment des molécules médicamenteuses, des acides aminés et des peptides, des saccharides, des colorants, des hydrocarbures, des hydrocarbures perfluorés et même des composés de poids moléculaire élevé tels que des protéines (par exemple, l'insuline humaine).Â
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- - October 18, 2024 60
EOTRH (Résorption dentaire odontoclastique équine et hypercémentose), en anglais : Equine odontoclastic tooth resorption and hypercementosis) . La maladie parodontale équine est une affection courante et douloureuse dont l’étiologie et la pathologie sont mal comprises.
EOTRH (equine odontoclastic tooth resorption and hypercementosis) affects about 5% of the horse population globally. Horses may also have inflamed gums and advanced gum disease.
- - October 09, 2024 39As you will be aware, the rehabilitation of equine tendon and ligament injuries is a complex process that requires a thorough understanding of the mechanical properties of soft tissues, and in particular the principles of fibre alignment and load limiting. These principles are crucial for promoting optimal healing, reducing the risk of re-injury, and restoring function in athletic horses
- - September 18, 2024 45
What is UTC?
Ultrasound Tissue Characterization (UTC) is a technology that uses a combination of both hardware and software to assess the fiber composition of your horse’s tendons and ligaments particularly in the distal limb.
A key part of this system is the UTC-Tracker, a precise tool that moves the ultrasound probe automatically along the length of a tendon, capturing images every 0.2 mm over a 12 cm area. These images are saved and processed in the operating system creating a 3D view of the tissue in the tendon or ligament.
With this 3D fibers model, vets can see the tendon (or other tissues) from different angles including transverse, sagittal, and coronal views, and a 3D rendered view. The user can also scroll through the entire model (like an X-ray). This helps to get a detailed look at the connective tissue the tendon sheath surrounding the tendon, and the inside of the tendon or ligament itself. This detailed view allows for accurate assessments of any damage or disintegration - - November 08, 2023 102
Equine Gastric Ulcer Syndrome is well known amongst equine veterinarians.Â
By Dr Michael Robinson
Aetiology
EGUS is best regarded as two separate entities: Equine Squamous Gastric Disease (ESGD) and Equine Glandular Gastric Disease (EGGD)1.
The two conditions may occur either independently or concurrently in the same horse. The presence or absence of one cannot be used as a predictor for the presence of absence of the other1.
ESGD is very common (between 11-95% depending on discipline and management)1,2. The causes of ESGD are well documented and it is known to be highly responsive to routine treatment with proton-pump inhibitors, such as omeprazole1.
EGGD is becoming more widely recognised (between 16-65% depending on discipline and management)1,2 as more veterinarians seek out the pyloric region of the stomach on routine gastrocopies. Visualisation of this region may be technically challenging but is an essential part of a full gastroscopy (Figure 1). The specific causes of EGGD are
- - October 11, 2023 183
The thoroughbred sire Brave Mansonnien, a rare genetic
The three founding stallions of the English thoroughbred breed are of foreign origin: Darley Arabian comes from Syria where he was acquired by an English merchant named Thomas Darley; Godolphin Arabian came from Morocco and had been offered to Louis XV by the caliph, he was then bought by the Englishman Edward Coke, while he was used to pull carts; Byerley Turk was a horse used by the Ottoman army, captured by an English soldier ...
The Male line of Byerley Turk      Â
The legend of Byerley Turk
The dark bay stallion was captured by the English captain Robert Byerley in 1687 during the siege of Buda (Hungary) by the Ottomans - hence its original name: Byerley's Turk. The soldier had noticed this very beautiful and very fast little horse. According to the legend, the stallion was also so fast and fiery that it took several days of tracking to succeed in capturing him. Captain Byerley used it during other campaigns in Ireland
- - August 18, 2023 38
Dangers of inbreeding and the necessity to preserve male lines in thoroughbreds. Dr B. Stoffel
This subject was presented at the recent 2023 general assembly of the EFTBA (European Federation of Thoroughbreds breeders Associations).
Inbreeding - a concern of many breeders - is the proportion of genes carried by the chromosomes inherited identically from both parents.
Situation of inbreeding in the Thoroughbred breed
The Thoroughbred breed has low genetic diversity compared to most other horse breeds, given its low population numbers and a trend of increasing inbreeding. This trend in the global Thoroughbred population has been reported for the past few decades and is unlikely to stop due to current breeding practices. 97% of the pedigrees of the horses included in a recent study include the paternal ancestor, Northern Dancer (1961) and 35% and 55% contain Saddler's Wells (1981) and Danehill (1986), respectively in Europe and Oceania.
Inbreeding can expose to harmful mutations: this leads
- - July 28, 2023 18
Hyaluronic acid
Sodium hyaluronate has been found present in the synovial fluid of all species studied. In humans it is also found in other soft connective tissues such as skin, umbilical cord, and vitreous humour as well as being present in lung, kidney, brain, and muscle tissues. Scientific understanding of the underlying properties of sodium hyaluronate started in 1934, when it was isolated from bovine vitreous humour Since the 1950s, the litterature concerning the potential therapeutic use of sodium hyaluronate in humans has grown.
The viscoelastic properties of synovial fluid in the joint are known to due to its sodium hyaluronate content. Changes in the lubricating properties of synovial fluid, lead to significant pain and loss of function.
In pathological conditions, due to acute and chronic inflammation, the synovial fluid no longer exhibits its normal rheological properties that protect the synovial tissue and cartilage from mechanical stress.
The concentration and molecular size